Plasma Lipidomic Profiling Using Mass Spectrometry for Multiple Sclerosis Diagnosis and Disease Activity Stratification (LipidMS)
doi: 10.3390/ijms25052483
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
doi: 10.1038/s41586-024-07079-8
In-situ architecture of the human prohibitin complex
doi: 10.1101/2024.02.14.579514
Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy
doi: 10.1016/j.ebiom.2024.104982
IntelliR: A comprehensive and standardized pipeline for automated profiling of higher cognition in mice
doi: 10.1101/2024.01.25.577156
Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
doi: 10.1016/j.neuron.2023.12.020
Long term follow-up in GAMT deficiency – Correlation of therapy regimen, biochemical and in vivo brain proton MR spectroscopy data
doi: 10.1016/j.ymgmr.2024.101053
L-Lactate Treatment at 24 h and 48 h after Acute Experimental Stroke Is Neuroprotective via Activation of the L-Lactate Receptor HCA1
doi: 10.3390/ijms25021232
Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach
doi: 10.1002/jimd.12713
CSF and venous blood flow from childhood to adulthood studied by real-time phase-contrast MRI
doi: 10.1007/s00381-024-06275-1
Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis
doi: 10.1212/wnl.0000000000207966
Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer’s disease
doi: 10.1101/2023.12.11.570514
Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain
doi: 10.1038/s41591-023-02644-6
Sekundärprophylaxe des ischämischen Schlaganfalls
doi: 10.1007/s00108-023-01615-w
Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies
doi: 10.1212/nxi.0000000000200176
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions
doi: 10.1038/s42255-023-00838-3
A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model
doi: 10.1038/s41593-023-01432-2
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation
doi: 10.1038/s41467-023-40982-8
Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis?
doi: 10.1111/nan.12935
Expanding the function of oligodendrocytes to brain energy metabolism
doi: 10.1016/j.conb.2023.102782
Erythropoietin re-wires cognition-associated transcriptional networks
doi: 10.1038/s41467-023-40332-8
Regulation of the programmed cell death protein 1/programmed cell death ligand 1axis in relapsing-remitting multiple sclerosis
doi: 10.1093/braincomms/fcad206
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease
doi: 10.1126/science.abn6366
Proceedings of the National Academy of Sciences of the United States of America
2023
Pubmed
Open AccessJournal Article
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging
doi: 10.1073/pnas.2302697120
Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury
doi: 10.1038/s41467-023-39447-9
Tipping points in neurodegeneration
doi: 10.1016/j.neuron.2023.05.031
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease
doi: 10.1038/s41593-023-01366-9
Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
doi: 10.1038/s41596-023-00831-w
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
doi: 10.1038/s41586-023-06120-6
2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca(2+) entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.
doi: 10.1016/j.bbamcr.2023.119485
Neural dynamics and architecture of the heading direction circuit in zebrafish.
doi: 10.1038/s41593-023-01308-5
Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex.
doi: 10.1016/j.neuron.2023.03.031
Myelination generates aberrant ultrastructure that is resolved by microglia.
doi: 10.1083/jcb.202204010
Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex
doi: 10.1101/2023.02.24.529840
Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress
doi: 10.1002/nep3.15
Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation
doi: 10.1212/nxi.0000000000200090
Membrane lipid remodeling modulates γ-secretase processivity
doi: 10.1016/j.jbc.2023.103027
Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency
doi: 10.15252/emmm.202114837
Targeting B Cells and Microglia in Multiple Sclerosis With Bruton Tyrosine Kinase Inhibitors
doi: 10.1001/jamaneurol.2022.5332
Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
doi: 10.1016/j.celrep.2021.109409
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain
doi: 10.1101/2022.05.09.491019
Targeted metabolomics revealed changes in phospholipids during the development of neuroinflammation in Abcd1tm1Kds mice and X‐linked adrenoleukodystrophy patients
doi: 10.1002/jimd.12389
LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders
doi: 10.3390/metabo11060347
Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study
doi: 10.3389/fmed.2021.644715
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
doi: 10.1038/s41593-021-00926-1
Neuronal replacement: Concepts, achievements, and call for caution
doi: 10.1016/j.conb.2021.03.014
Correction: Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
doi: 10.1016/j.celrep.2021.109571
TUNAR lncRNA Encodes a Microprotein that Regulates Neural Differentiation and Neurite Formation by Modulating Calcium Dynamics
doi: 10.3389/fcell.2021.747667
Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation
doi: 10.3389/fimmu.2021.800128
White matter integrity in mice requires continuous myelin synthesis at the inner tongue
doi: 10.1038/s41467-022-28720-y
Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43
doi: 10.7554/elife.75230
Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
doi: 10.3389/fcell.2021.747699
Neural labeling and manipulation by neonatal intraventricular viral injection in mice
doi: 10.1016/j.xpro.2021.101081
Semaphorin7A: its role in the control of serotonergic circuits and functional recovery following spinal cord injury
doi: 10.4103/1673-5374.324828
Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling
doi: 10.1038/s41593-022-01023-7
Proceedings of the National Academy of Sciences of the United States of America
2022
Pubmed
Open AccessJournal Article
The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans
doi: 10.1073/pnas.2206208119
Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation
doi: 10.1007/s00109-022-02202-6
Cellular and Molecular Determinants of Retinal Cell Fate
doi: 10.1146/annurev-vision-100820-103154
Brain injury environment critically influences the connectivity of transplanted neurons
doi: 10.1126/sciadv.abg9445
Probing cell identity hierarchies by fate titration and collision during direct reprogramming
doi: 10.15252/msb.202211129
Reparative inflammation in multiple sclerosis
doi: 10.1016/j.smim.2022.101630
Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis
doi: 10.1007/s00401-022-02442-3
The Gut-Brain Axis in Inflammatory Bowel Disease – Current and Future Perspectives
doi: 10.3390/ijms22168870
The Aryl Hydrocarbon Receptor–Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis
doi: 10.1212/nxi.0000000000001043
Identification of covalent modifications regulating immune signaling complex composition and phenotype
doi: 10.15252/msb.202010125
Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in mice
doi: 10.1093/cvr/cvab359
Niwaki Instead of Random Forests: Targeted Serial Sectioning Scanning Electron Microscopy With Reimaging Capabilities for Exploring Central Nervous System Cell Biology and Pathology
doi: 10.3389/fnana.2021.732506
Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
doi: 10.1038/s41590-020-0666-9
Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury
doi: 10.15252/emmm.202216111
Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status
doi: 10.1016/j.xcrm.2022.100877
Coordinated neurostimulation promotes circuit rewiring and unlocks recovery after spinal cord injury
doi: 10.1084/jem.20220615
T cells modulate the microglial response to brain ischemia
doi: 10.7554/elife.82031
MCU controls melanoma progression through a redox‐controlled phenotype switch
doi: 10.15252/embr.202254746
Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity
doi: 10.1038/s41590-021-00948-8
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis
doi: 10.1111/bpa.13136
Plasticity of callosal neurons in the contralesional cortex following traumatic brain injury
doi: 10.4103/1673-5374.360167
Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology
doi: 10.1038/s41590-022-01360-6
TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury
doi: 10.1038/s41593-022-01199-y
Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity
doi: 10.1101/2022.11.21.517320
A deep learning-based toolbox for Automated Limb Motion Analysis (ALMA) in murine models of neurological disorders
doi: 10.1038/s42003-022-03077-6
Factors predisposing to humoral autoimmunity against brain-antigens in health and disease Analysis of 49 autoantibodies in over 7000 subjects
doi: 10.1016/j.bbi.2022.10.016
CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities
doi: 10.1016/j.neuron.2022.09.023
CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
doi: 10.1038/s41593-022-01183-6
Ganglioside lipidomics of central nervous system myelination using direct infusion shotgun mass spectrometry
doi: 10.1016/j.isci.2022.105323
For decades against the mainstream – from erythropoietin and hypoxia as novel treatment strategies to deep phenotyping in neuropsychiatric disorders
doi: 10.1016/j.psychres.2022.114854
Ketogenic diet uncovers differential metabolic plasticity of brain cells
doi: 10.1126/sciadv.abo7639
DNA-PAINT MINFLUX nanoscopy
doi: 10.1038/s41592-022-01577-1
Autoantibodies against NMDAR subunit NR1 disappear from blood upon anesthesia
doi: 10.1016/j.bbih.2022.100494
IL-24 intrinsically regulates Th17 cell pathogenicity in mice
doi: 10.1084/jem.20212443
P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica
doi: 10.1007/s13311-022-01269-w
Distinct roles of the meningeal layers in CNS autoimmunity
doi: 10.1038/s41593-022-01108-3
Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage
doi: 10.1038/s41467-022-31054-4
CNS Treg cells have alternative functions but run on conventional fuel
doi: 10.1038/s41590-022-01201-6
Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury
doi: 10.1038/s41467-022-29992-0
Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation
doi: 10.1172/jci.insight.154824
Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno‐Associated Viral Vector rAAV9P1
doi: 10.1002/advs.202104979
Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance
doi: 10.1038/s41380-022-01551-5
Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS
doi: 10.1126/scitranslmed.abl6058
Size‐Selective Transfer of Lipid Nanoparticle‐Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury
doi: 10.1002/smll.202200302
Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis
doi: 10.1212/nxi.0000000000001159
