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2023
- Hosang L, Löhndorf A, Dohle W, Rosche A, Marry S, Diercks BP, Müller-Kirschbaum LC, Flügel LT, Potter BVL, Odoardi F, Guse AH, Flügel A. 2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca2+ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.. Biochim Biophys Acta Mol Cell Res. 2023 May 6;1870(6):119485. doi: 10.1016/j.bbamcr.2023.119485. Epub ahead of print. PMID: 37150482. (Pubmed)
- Biljecki M, Eisenhut K, Beltrán E, Winklmeier S, Mader S, Thaller A, Eichhorn P, Steininger P, Flierl-Hecht A, Lewerenz J, Kümpfel T, Kerschensteiner M, Meinl E, Thaler FS. Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation. Neurol Neuroimmunol Neuroinflamm. 2023 Feb 23;10(3):e200090. doi: 10.1212/NXI.0000000000200090. PMID: 36823135; PMCID: PMC9969496. (Pubmed)
- Arinrad S, Wilke JBH, Seelbach A, Doeren J, Hindermann M, Butt UJ, Steixner-Kumar AA, Spieth L, Ronnenberg A, Pan H, Berghoff SA, Hollmann M, Lühder F, Nave KA, Bechter K, Ehrenreich H. NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance. Mol Psychiatry. 2022 Dec;27(12):4974-4983. doi: 10.1038/s41380-021-01392-8. Epub 2021 Dec 6. PMID: 34866134; PMCID: PMC9763107. (Pubmed)
- Mezydlo A, Treiber N, Ullrich Gavilanes EM, Eichenseer K, Ancău M, Wens A, Ares Carral C, Schifferer M, Snaidero N, Misgeld T, Kerschensteiner M. Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex.. Neuron. 2023 Apr 17:S0896-6273(23)00227-1. doi: 10.1016/j.neuron.2023.03.031. Epub ahead of print. PMID: 37071991. (Pubmed)
- Petrucco L, Lavian H, Wu YK, Svara F, Štih V, Portugues R. Neural dynamics and architecture of the heading direction circuit in zebrafish.. Nat Neurosci. 2023 May;26(5):765-773. doi: 10.1038/s41593-023-01308-5. Epub 2023 Apr 24. PMID: 37095397; PMCID: PMC10166860. (Pubmed)
- Aljović A, Jacobi A, Marcantoni M, Kagerer F, Loy K, Kendirli A, Bräutigam J, Fabbio L, Van Steenbergen V, Pleśniar K, Kerschensteiner M, Bareyre FM. Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury. EMBO Mol Med. 2023 Feb 8;15(2):e16111. doi: 10.15252/emmm.202216111. Epub 2023 Jan 5. PMID: 36601738; PMCID: PMC9906383. (Pubmed)
- Schlotawa L, Tyka K, Kettwig M, Ahrens-Nicklas RC, Baud M, Berulava T, Brunetti-Pierri N, Gagne A, Herbst ZM, Maguire JA, Monfregola J, Pena T, Radhakrishnan K, Schröder S, Waxman EA, Ballabio A, Dierks T, Fischer A, French DL, Gelb MH, Gärtner J. Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency. EMBO Mol Med. 2023 Mar 8;15(3):e14837. doi: 10.15252/emmm.202114837. Epub 2023 Feb 15. PMID: 36789546; PMCID: PMC9994482. (Pubmed)
- Dybowski S, Torke S, Weber MS. Targeting B Cells and Microglia in Multiple Sclerosis With Bruton Tyrosine Kinase Inhibitors: A Review. JAMA Neurol. 2023 Apr 1;80(4):404-414. doi: 10.1001/jamaneurol.2022.5332. PMID: 36780171. (Pubmed)
- Dawkins E, Derks RJE, Schifferer M, Trambauer J, Winkler E, Simons M, Paquet D, Giera M, Kamp F, Steiner H. Membrane lipid remodeling modulates γ-secretase processivity. J Biol Chem. 2023 Feb 16;299(4):103027. doi: 10.1016/j.jbc.2023.103027. Epub ahead of print. PMID: 36805335; PMCID: PMC10070668. (Pubmed)
- Hannelore Ehrenreich MD, DVM, Max Gassmann DVM, Luise Poustka MD, Martin Burtscher MD, Peter Hammermann PhD, Anna-Leena Sirén MD, PhD, Klaus-Armin Nave PhD, Kamilla Miskowiak PhD. Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress. (Link)
- Djannatian M, Radha S, Weikert U, Safaiyan S, Wrede C, Deichsel C, Kislinger G, Rhomberg A, Ruhwedel T, Campbell DS, van Ham T, Schmid B, Hegermann J, Möbius W, Schifferer M, Simons M. Myelination generates aberrant ultrastructure that is resolved by microglia. J Cell Biol. 2023 Mar 6;222(3):e202204010. doi: 10.1083/jcb.202204010. Epub 2023 Jan 13. PMID: 36637807; PMCID: PMC9856851. (Pubmed)
2022
- Cantuti-Castelvetri L, Gokce O, Simons M. Reparative inflammation in multiple sclerosis. Semin Immunol. 2022 Jan;59:101630. doi: 10.1016/j.smim.2022.101630. Epub 2022 Jun 22. PMID: 35750551. (Pubmed)
- Hersbach BA, Fischer DS, Masserdotti G, Deeksha, Mojžišová K, Waltzhöni T, Rodriguez-Terrones D, Heinig M, Theis FJ, Götz M, Stricker SH. Probing cell identity hierarchies by fate titration and collision during direct reprogramming. Mol Syst Biol. 2022 Sep;18(9):e11129. doi: 10.15252/msb.202211129. PMID: 36106915; PMCID: PMC9476893. (Pubmed)
- Ehrenreich H. For decades against the mainstream - From erythropoietin and hypoxia as novel treatment strategies to deep phenotyping in neuropsychiatric disorders. Psychiatry Res. 2022 Nov;317:114854. doi: 10.1016/j.psychres.2022.114854. Epub 2022 Sep 17. PMID: 36170796; PMCID: PMC7613706. (Pubmed)
- Aly L, Noll C, Wicklein R, Wolf E, Romahn EF, Wauschkuhn J, Hosari S, Mardin C, Berthele A, Hemmer B, Korn T, Knier B. Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2022 Mar 17;9(3):e1159. doi: 10.1212/NXI.0000000000001159. PMID: 35301260; PMCID: PMC8931743. (Pubmed)
- Liu T, Stephan T, Chen P, Keller-Findeisen J, Chen J, Riedel D, Yang Z, Jakobs S, Chen Z. Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain. Proc Natl Acad Sci U S A. 2022 Dec 27;119(52):e2215799119. doi: 10.1073/pnas.2215799119. Epub 2022 Dec 19. PMID: 36534799; PMCID: PMC9907107. (Pubmed)
- Mitsdoerffer M, Aly L, Barz M, Engleitner T, Sie C, Delbridge C, Lepennetier G, Öllinger R, Pfaller M, Wiestler B, Rad R, Meyer B, Knier B, Schmidt-Graf F, Gempt J, Korn T. The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206208119. doi: 10.1073/pnas.2206208119. Epub 2022 Aug 15. PMID: 35969754; PMCID: PMC9407554. (Pubmed)
- Ehrenreich H, Garcia-Agudo LF, Steixner-Kumar AA, Wilke JBH, Butt UJ. Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance. Mol Psychiatry. 2022 May;27(5):2372-2379. doi: 10.1038/s41380-022-01551-5. Epub 2022 Apr 12. PMID: 35414656; PMCID: PMC9004453. (Pubmed)
- Thomas J, Martinez-Reza MF, Thorwirth M, Zarb Y, Conzelmann KK, Hauck SM, Grade S, Götz M. Excessive local host-graft connectivity in aging and amyloid-loaded brain. Sci Adv. 2022 Jun 10;8(23):eabg9287. doi: 10.1126/sciadv.abg9287. Epub 2022 Jun 10. PMID: 35687689; PMCID: PMC9187230. (Pubmed)
- Düking T, Spieth L, Berghoff SA, Piepkorn L, Schmidke AM, Mitkovski M, Kannaiyan N, Hosang L, Scholz P, Shaib AH, Schneider LV, Hesse D, Ruhwedel T, Sun T, Linhoff L, Trevisiol A, Köhler S, Pastor AM, Misgeld T, Sereda M, Hassouna I, Rossner MJ, Odoardi F, Ischebeck T, de Hoz L, Hirrlinger J, Jahn O, Saher G. Ketogenic diet uncovers differential metabolic plasticity of brain cells. Sci Adv. 2022 Sep 16;8(37):eabo7639. doi: 10.1126/sciadv.abo7639. Epub 2022 Sep 16. PMID: 36112685; PMCID: PMC9481126. (Pubmed)
- Grade S, Thomas J, Zarb Y, Thorwirth M, Conzelmann KK, Hauck SM, Götz M. Brain injury environment critically influences the connectivity of transplanted neurons. Sci Adv. 2022 Jun 10;8(23):eabg9445. doi: 10.1126/sciadv.abg9445. Epub 2022 Jun 10. PMID: 35687687; PMCID: PMC9187233. (Pubmed)
- Khalin I, Adarsh N, Schifferer M, Wehn A, Groschup B, Misgeld T, Klymchenko A, Plesnila N. Size-Selective Transfer of Lipid Nanoparticle-Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury. Small. 2022 May;18(18):e2200302. doi: 10.1002/smll.202200302. Epub 2022 Apr 5. PMID: 35384294. (Pubmed)
- Herwerth M, Kenet S, Schifferer M, Winkler A, Weber M, Snaidero N, Wang M, Lohrberg M, Bennett JL, Stadelmann C, Hemmer B, Misgeld T. A new form of axonal pathology in a spinal model of neuromyelitis optica. Brain. 2022 Jun 3;145(5):1726-1742. doi: 10.1093/brain/awac079. PMID: 35202467; PMCID: PMC9166560. (Pubmed)
- Bader JM, Deigendesch N, Misch M, Mann M, Koch A, Meissner F. Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status. Cell Rep Med. 2023 Jan 17;4(1):100877. doi: 10.1016/j.xcrm.2022.100877. Epub 2022 Dec 29. PMID: 36584682; PMCID: PMC9873829. (Pubmed)
- Bauer A, Puglisi M, Nagl D, Schick JA, Werner T, Klingl A, El Andari J, Hornung V, Kessler H, Götz M, Grimm D, Brack-Werner R. Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1. Adv Sci (Weinh). 2022 May;9(16):e2104979. doi: 10.1002/advs.202104979. Epub 2022 Apr 10. PMID: 35398994; PMCID: PMC9165502. (Pubmed)
- Van Steenbergen V, Burattini L, Trumpp M, Fourneau J, Aljović A, Chahin M, Oh H, D'Ambra M, Bareyre FM. Coordinated neurostimulation promotes circuit rewiring and unlocks recovery after spinal cord injury. J Exp Med. 2023 Mar 6;220(3):e20220615. doi: 10.1084/jem.20220615. Epub 2022 Dec 26. PMID: 36571760; PMCID: PMC9794600. (Pubmed)
- Sie C, Kant R, Peter C, Muschaweckh A, Pfaller M, Nirschl L, Moreno HD, Chadimová T, Lepennetier G, Kuhlmann T, Öllinger R, Engleitner T, Rad R, Korn T. IL-24 intrinsically regulates Th17 cell pathogenicity in mice. J Exp Med. 2022 Aug 1;219(8):e20212443. doi: 10.1084/jem.20212443. Epub 2022 Jul 12. PMID: 35819408; PMCID: PMC9280194. (Pubmed)
- Meschkat M, Steyer AM, Weil MT, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Phan NTN, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave KA, Möbius W. White matter integrity in mice requires continuous myelin synthesis at the inner tongue. Nat Commun. 2022 Mar 4;13(1):1163. doi: 10.1038/s41467-022-28720-y. PMID: 35246535; PMCID: PMC8897471. (Pubmed)
- Lutz K, Musumeci A, Sie C, Dursun E, Winheim E, Bagnoli J, Ziegenhain C, Rausch L, Bergen V, Luecken MD, Oostendorp RAJ, Schraml BU, Theis FJ, Enard W, Korn T, Krug AB. Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage. Nat Commun. 2022 Jun 16;13(1):3456. doi: 10.1038/s41467-022-31054-4. PMID: 35705536; PMCID: PMC9200809. (Pubmed)
- Empl L, Chovsepian A, Chahin M, Kan WYV, Fourneau J, Van Steenbergen V, Weidinger S, Marcantoni M, Ghanem A, Bradley P, Conzelmann KK, Cai R, Ghasemigharagoz A, Ertürk A, Wagner I, Kreutzfeldt M, Merkler D, Liebscher S, Bareyre FM. Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury. Nat Commun. 2022 May 12;13(1):2659. doi: 10.1038/s41467-022-29992-0. PMID: 35551446; PMCID: PMC9098892. (Pubmed)
- Franklin RJM, Simons M. CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities. Neuron. 2022 Nov 2;110(21):3549-3565. doi: 10.1016/j.neuron.2022.09.023. Epub 2022 Oct 12. PMID: 36228613. (Pubmed)
- Liesche-Starnecker F, Schifferer M, Schlegel J, Vollmuth Y, Rubbenstroth D, Delbridge C, Gempt J, Lorenzl S, Schnurbus L, Misgeld T, Rosati M, Beer M, Matiasek K, Wunderlich S, Finck T. Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis. Acta Neuropathol. 2022 Aug;144(2):377-379. doi: 10.1007/s00401-022-02442-3. Epub 2022 Jun 3. PMID: 35657496; PMCID: PMC9164175. (Pubmed)
- Daguano Gastaldi V, Bh Wilke J, Weidinger CA, Walter C, Barnkothe N, Teegen B, Luessi F, Stöcker W, Lühder F, Begemann M, Zipp F, Nave KA, Ehrenreich H. Factors predisposing to humoral autoimmunity against brain-antigens in health and disease: Analysis of 49 autoantibodies in over 7000 subjects. Brain Behav Immun. 2023 Feb;108:135-147. doi: 10.1016/j.bbi.2022.10.016. Epub 2022 Oct 30. PMID: 36323361. (Pubmed)
- Teller J, Jung C, Wilke JBH, Schimmelpfennig SD, Hindermann M, Hinken L, Gabriel MM, Fegbeutel C, Schäfer A, Laser H, Lichtinghagen R, Worthmann H, Weissenborn K, Ehrenreich H. Autoantibodies against NMDAR subunit NR1 disappear from blood upon anesthesia. Brain Behav Immun Health. 2022 Aug 4;24:100494. doi: 10.1016/j.bbih.2022.100494. PMID: 35965838; PMCID: PMC9372600. (Pubmed)
- Vincenti I, Page N, Steinbach K, Yermanos A, Lemeille S, Nunez N, Kreutzfeldt M, Klimek B, Di Liberto G, Egervari K, Piccinno M, Shammas G, Mariotte A, Fonta N, Liaudet N, Shlesinger D, Liuzzi AR, Wagner I, Saadi C, Stadelmann C, Reddy S, Becher B, Merkler D. Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS. Sci Transl Med. 2022 Apr 13;14(640):eabl6058. doi: 10.1126/scitranslmed.abl6058. Epub 2022 Apr 13. PMID: 35417190. (Pubmed)
- Kaya T, Mattugini N, Liu L, Ji H, Cantuti-Castelvetri L, Wu J, Schifferer M, Groh J, Martini R, Besson-Girard S, Kaji S, Liesz A, Gokce O, Simons M. CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging. Nat Neurosci. 2022 Nov;25(11):1446-1457. doi: 10.1038/s41593-022-01183-6. Epub 2022 Oct 24. PMID: 36280798; PMCID: PMC9630119. (Pubmed)
- Merlini A, Haberl M, Strauß J, Hildebrand L, Genc N, Franz J, Chilov D, Alitalo K, Flügel-Koch C, Stadelmann C, Flügel A, Odoardi F. Distinct roles of the meningeal layers in CNS autoimmunity. Nat Neurosci. 2022 Jul;25(7):887-899. doi: 10.1038/s41593-022-01108-3. Epub 2022 Jun 30. PMID: 35773544. (Pubmed)
- Xiao Y, Petrucco L, Hoodless LJ, Portugues R, Czopka T. Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling. Nat Neurosci. 2022 Mar;25(3):280-284. doi: 10.1038/s41593-022-01023-7. Epub 2022 Mar 3. PMID: 35241802; PMCID: PMC8904260. (Pubmed)
- Zambusi A, Novoselc KT, Hutten S, Kalpazidou S, Koupourtidou C, Schieweck R, Aschenbroich S, Silva L, Yazgili AS, van Bebber F, Schmid B, Möller G, Tritscher C, Stigloher C, Delbridge C, Sirko S, Günes ZI, Liebscher S, Schlegel J, Aliee H, Theis F, Meiners S, Kiebler M, Dormann D, Ninkovic J. TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury. Nat Neurosci. 2022 Dec;25(12):1608-1625. doi: 10.1038/s41593-022-01199-y. Epub 2022 Nov 24. PMID: 36424432. (Pubmed)
- Korn T. CNS Treg cells have alternative functions but run on conventional fuel. Nat Immunol. 2022 Jun;23(6):818-819. doi: 10.1038/s41590-022-01201-6. PMID: 35618830. (Pubmed)
- Haimon Z, Frumer GR, Kim JS, Trzebanski S, Haffner-Krausz R, Ben-Dor S, Porat Z, Muschaweckh A, Chappell-Maor L, Boura-Halfon S, Korn T, Jung S. Cognate microglia-T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology. Nat Immunol. 2022 Dec;23(12):1749-1762. doi: 10.1038/s41590-022-01360-6. Epub 2022 Dec 1. PMID: 36456736. (Pubmed)
- Ostersehlt LM, Jans DC, Wittek A, Keller-Findeisen J, Inamdar K, Sahl SJ, Hell SW, Jakobs S. DNA-PAINT MINFLUX nanoscopy. Nat Methods. 2022 Sep;19(9):1072-1075. doi: 10.1038/s41592-022-01577-1. Epub 2022 Sep 1. PMID: 36050490; PMCID: PMC9467913. (Pubmed)
- Hosang L, Canals RC, van der Flier FJ, Hollensteiner J, Daniel R, Flügel A, Odoardi F. The lung microbiome regulates brain autoimmunity. Nature. 2022 Mar;603(7899):138-144. doi: 10.1038/s41586-022-04427-4. Epub 2022 Feb 23. PMID: 35197636. (Pubmed)
- Petridou E, Godinho L. Cellular and Molecular Determinants of Retinal Cell Fate. Annu Rev Vis Sci. 2022 Sep 15;8:79-99. doi: 10.1146/annurev-vision-100820-103154. PMID: 36108104. (Pubmed)
- Galbusera R, Bahn E, Weigel M, Schaedelin S, Franz J, Lu PJ, Barakovic M, Melie-Garcia L, Dechent P, Lutti A, Sati P, Reich DS, Nair G, Brück W, Kappos L, Stadelmann C, Granziera C. Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis. Brain Pathol. 2022 Dec 8:e13136. doi: 10.1111/bpa.13136. Epub ahead of print. PMID: 36480267. (Pubmed)
- Gil-Pulido J, Amézaga N, Jorgacevic I, Manthey HD, Rösch M, Brand T, Cidlinsky P, Schäfer S, Beilhack A, Saliba AE, Lorenz K, Boon L, Prinz I, Waisman A, Korn T, Cochain C, Zernecke A. Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in mice. Cardiovasc Res. 2022 Nov 10;118(14):2932-2945. doi: 10.1093/cvr/cvab359. PMID: 34897380. (Pubmed)
- Sanchez-Gonzalez R, Koupourtidou C, Lepko T, Zambusi A, Novoselc KT, Durovic T, Aschenbroich S, Schwarz V, Breunig CT, Straka H, Huttner HB, Irmler M, Beckers J, Wurst W, Zwergal A, Schauer T, Straub T, Czopka T, Trümbach D, Götz M, Stricker SH, Ninkovic J. Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain. Cells. 2022 Feb 2;11(3):520. doi: 10.3390/cells11030520. PMID: 35159329; PMCID: PMC8834209. (Pubmed)
- Liebich A, Schmid N, Koupourtidou C, Herrmann C, Dietrich KG, Welter H, Ninkovic J, Mayerhofer A. The Molecular Signature of Human Testicular Peritubular Cells Revealed by Single-Cell Analysis. Cells. 2022 Nov 19;11(22):3685. doi: 10.3390/cells11223685. PMID: 36429113; PMCID: PMC9688777. (Pubmed)
- Aljovic A, Zhao S, Chahin M, de la Rosa C, Van Steenbergen V, Kerschensteiner M, Bareyre FM. A deep learning-based toolbox for Automated Limb Motion Analysis (ALMA) in murine models of neurological disorders. Commun Biol. 2022 Feb 15;5(1):131. doi: 10.1038/s42003-022-03077-6. PMID: 35169263; PMCID: PMC8847458. (Pubmed)
- Benakis C, Simats A, Tritschler S, Heindl S, Besson-Girard S, Llovera G, Pinkham K, Kolz A, Ricci A, Theis FJ, Bittner S, Gökce Ö, Peters A, Liesz A. T cells modulate the microglial response to brain ischemia. Elife. 2022 Dec 13;11:e82031. doi: 10.7554/eLife.82031. PMID: 36512388; PMCID: PMC9747154. (Pubmed)
- Arinrad S, Depp C, Siems SB, Sasmita AO, Eichel MA, Ronnenberg A, Hammerschmidt K, Lüders KA, Werner HB, Ehrenreich H, Nave KA. Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity. Elife. 2023 Mar 9;12:e70792. doi: 10.7554/eLife.70792. PMID: 36892455; PMCID: PMC9998085. (Pubmed)
- Heo D, Ling JP, Molina-Castro GC, Langseth AJ, Waisman A, Nave KA, Möbius W, Wong PC, Bergles DE. Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43. Elife. 2022 Mar 21;11:e75230. doi: 10.7554/eLife.75230. PMID: 35311646; PMCID: PMC8970587. (Pubmed)
- Stejerean-Todoran I, Zimmermann K, Gibhardt CS, Vultur A, Ickes C, Shannan B, Bonilla Del Rio Z, Wölling A, Cappello S, Sung HM, Shumanska M, Zhang X, Nanadikar M, Latif MU, Wittek A, Lange F, Waters A, Brafford P, Wilting J, Urlaub H, Katschinski DM, Rehling P, Lenz C, Jakobs S, Ellenrieder V, Roesch A, Schön MP, Herlyn M, Stanisz H, Bogeski I. MCU controls melanoma progression through a redox-controlled phenotype switch. EMBO Rep. 2022 Nov 7;23(11):e54746. doi: 10.15252/embr.202254746. Epub 2022 Sep 26. PMID: 36156348; PMCID: PMC9638851. (Pubmed)
- Noll C, Hiltensperger M, Aly L, Wicklein R, Afzali AM, Mardin C, Gasperi C, Berthele A, Hemmer B, Korn T, Knier B. Association of the retinal vasculature, intrathecal immunity, and disability in multiple sclerosis. Front Immunol. 2022 Nov 11;13:997043. doi: 10.3389/fimmu.2022.997043. PMID: 36439131; PMCID: PMC9695398. (Pubmed)
- Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Tsaktanis T, Naumann U, Rothhammer V. Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation. Front Immunol. 2022 Jan 3;12:800128. doi: 10.3389/fimmu.2021.800128. PMID: 35046956; PMCID: PMC8762329. (Pubmed)
- Arends M, Weber M, Papan C, Damm M, Surma MA, Spiegel C, Djannatian M, Li S, Connell L, Johannes L, Schifferer M, Klose C, Simons M. Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry. iScience. 2022 Oct 10;25(11):105323. doi: 10.1016/j.isci.2022.105323. PMID: 36310581; PMCID: PMC9615322. (Pubmed)
- Linnerbauer M, Lößlein L, Vandrey O, Tsaktanis T, Beer A, Naumann UJ, Panier F, Beyer T, Nirschl L, Kuramatsu JB, Winkler J, Quintana FJ, Rothhammer V. Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation. JCI Insight. 2022 Apr 8;7(7):e154824. doi: 10.1172/jci.insight.154824. PMID: 35393953; PMCID: PMC9057609. (Pubmed)
- Maisam Afzali A, Stüve L, Pfaller M, Aly L, Steiger K, Knier B, Korn T. Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation. J Mol Med (Berl). 2022 Jun;100(6):933-946. doi: 10.1007/s00109-022-02202-6. Epub 2022 May 10. PMID: 35536323; PMCID: PMC9166880. (Pubmed)
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- Riera-Tur I, Schäfer T, Hornburg D, Mishra A, da Silva Padilha M, Fernández-Mosquera L, Feigenbutz D, Auer P, Mann M, Baumeister W, Klein R, Meissner F, Raimundo N, Fernández-Busnadiego R, Dudanova I. Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity. Life Sci Alliance. 2021 Dec 21;5(3):e202101185. doi: 10.26508/lsa.202101185. PMID: 34933920; PMCID: PMC8711852. (Pubmed)
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2021
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2020
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